The Effect of Low Power He-Ne Laser on Growth and Activity of Proteinase in Dermatophyte Trichophyton mentagrophytes

Abstract

This study was carried out to evaluate the effect of low power a semi-conductor He-Ne Laser 4 mw power with 635 nm length on the growth and activity of enzyme proteinase for dermatophyte Trichophyton mentagrophytes. Skin samples of 22 patients were collecting; those patients were suffering from dermatophytsis caused by the dermatophytes, three isolates were diagnosed a dermatophytes group was caused by T. mentagrophytes. The results showed the effects of He-Ne Laser rays on the growth of ideal isolate in solid and liquid media (when the viability measure in applied on the fungal cells), by exposing the three isolates to Laser radiation in different periods of 10-20 second duration, but the other two isolates gave negative results because of their weak growth. On the other hand, the process of sporulation was affected within 10-20 second radiation time; in this duration He-Ne Laser rays also affected the activity of proteinase enzyme. The results showed that the He-Ne Laser ray within 10-20 second radiation was effective in treatment of experimental skin infected with T. mentagrophytes.